I started a thread a while back asking people what calibre they would have if they could only have one rifle. The .243 was the easy winner on its own, but counting all the .220 CFs together, that's Hornet, .222, .223, .22-250, and .220 Swift, they just pipped the .243. The rimmies were a poor third.
Yer pays yer money and yer takes yer choice.