All my cf rifles calibers I successfully down loaded for small game getting.
It can be done but in all honesty the rifle to go for and or calibre if you could only have one would have to be based on what someone shoots the most.
So for me my wmr covers it all and heck, it even put a fallow out of its misery after some idiot who can't shoot straight broke a hind leg.
Personally, I could not forsake my small game hunting with a suitable rifle for something for an occasional deer hunt.
If it ever came to the scenario suggested well....there are other means.