only ever used it on a saluki/grey pup i had years ago,good healthy pup,or so it seemed,got home and occasionally it was shitting with small amounts of blood in it.after a trip to the vet and a couple of weeks of unnecessary pills,was told to put her on chappie,very good for a young dog with this condition and worked almost immediately,the previous owner obviously feeding it something far to rich/strong whatever, for it,so as i say used it once with good effect