just read your thread above, and sounds like you all suffered , not just your sister, sad to read mate. when i was working at my local brewery , i worked with a bloke who was a (manic depressive ) i worked with him for 10 years, and he was a type of person that never really smiled , and always had a bleak out look to life . i used to go mad at him some days, and told him to get a grip and snap out of it. But he never did change in 10 years, i did feel sorry for him really , as he just could never be happy with life . it is a illness deff , i get low alot with bad back ive had since the 8