I've been running dogs for 20 years and never heard or seen one being ran so can't really comment, doberman cross greys/lurchers I have seen running but they weren't my scene, I even had a bullmastiff/wolfhound out of a accidental mating and at 11 months old was far too big and heavy so it went to a pet home (worst ever cross I have tried and I will admit that)
i know a lad in Oz who uses wolfhounds\bullmastiffs on hogs but agreed way to big for anything over in the UK.