I've mentioned it on here, years ago, but I once owned a GSD bitch, years ago. She developed a severe colitis. At the time there was no cure.
I put a lot of care and training into her, so wasn't prepared for the vet's recommendation to have her pts, at about 5 months.
Anyway, a mate of mine took her off me, a while later, to guard his allotment and a few kennels.
One of his lurchers, collie/grey xwhip/grey mated with her, and he kept a bitch pup from that litter, and lamped her with a fair amount of success.
A couple of years later, he bred her with the sires litter broth