Just a small oppinion
Savage makes a nice .22-250, heavy barrel, 1 in 12 twist. It is a nice flat shooting, good grouping rifle.
Use the proper powder and bullet for your cartriges and it is an excellent all round rifle. Can take all rodents, rabits, foxes, wolves, wolverine, black bear, and caribou. Although on really windy days, I will take the .30-378 for caribou, moose and bear.
Personally, I feel that if a person were to get a good trustworthy rifle in the 5-7mm range, then it really depends on your reloading choices.