Hello Ditch shitter
I once had the pleasure of talking to a jeweller from Galveston, over a mexican meal and talk of wetbacks and bobtails; his take on your query is to use a Texas Heart shot.
You must have plenty of caliber for this shot as it entails using the ring piece as your aiming point. The round enters soft tissue continues through soft tissue all its way into the chest cavity where it does terminal and instant damage to all the vitals, lungs and heart. High shots disengage the spine, low shots reach deeper into the chest cavity.
I cannot claim to have used it on anything large, sq